Defending champion Naomi Osaka has been knocked out of the Australian Open.
She lost in three sets to American Amanda Anisimova, who prevailed 4-6, 6-3, 7-6.
Top seed Ash Barty is into the fourth round in Melbourne following a straight sets win over Camila Giorgi.
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Third seed Alexander Zverev is into the last 16 after a straight sets win over Radu Albot.