Arsenal have restored their 8 point advantage at the top of the Premier League.
They eased to a 4-1 win at home to Leeds United, with Gabriel Jesus getting a brace.
Manchester City kept the pressure on their title rivals with a 4-1 comeback victory over Liverpool.
Roy Hodgson's second spell in charge of Crystal Palace got off to a winning start.
Jean-Philippe Mateta's 94th minute goal helped them beat Leicester 2-1.
Alexis Mac Allister's last minute penalty secured Brighton a 3-all draw with fellow European qualification chasers Brentford.
Bournemouth moved out of the relegation places with a 2-1 success over Fulham.
Nottingham Forest drew 1-all with fellow strugglers Wolves.
Chelsea host Aston Vila in the late kick-off.