Manchester City can move within two points of leaders Arsenal this evening.
They face a tricky trip to Leeds United, who have only lost once in their last seven games at Elland Road.
Kick-off is at half-five.
At 3 o'clock, Brentford head coach Keith Andrews will be hoping to celebrate the signing of a new long-term deal by winning at Burnley.
Liverpool continue their push for a top-four finish when they host West Ham, who are bidding for a first win at Anfield since 2015.
Newcastle and Everton will look to arrest their respective poor runs in the league, when they meet at St James's Park.
The early game sees Sunderland go to Bournemouth, for a half 12 start.
Bottom side Wolves have just their second Premier League win of the season following a 2-nil victory at home to third-placed Aston Villa.
The strugglers scored in the second half - their 19th top flight goal of the season.
Wanderers are now on 13 points - 2 more than Derby's lowest tally.
