FA Cup holders Crystal Palace have suffered one of the biggest upsets in the competition's history.
They went out in the third round following a 2-1 defeat at non-league Macclesfield.
League Cup holders Newcastle and Bournemouth are in a penalty shootout after their tie finished 3-3 after extra time.
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Earlier, Everton missed all their penalties as Sunderland went through on spot kicks.
Fulham came back to beat Middlesbrough 3-1, while Manchester City thrashed Exeter 10-1.
Tottenham face Aston Villa in around 45-minutes, before Liam Rosenior leads Chelsea at Charlton later tonight.
