Arsenal have avoided a scare to beat Mansfield 2-1 and progress to the quarter-finals of the FA Cup.
The Premier League leaders were pegged back by the League One side in the second-half, before Eberechi Eze got the winning goal.
Wrexham look to cause an upset against Chelsea in the early evening kick-off.
That's followed by an even later clash between Newcastle and Manchester City.
Millwall have beaten Hull 3-1 to move within a point of the automatic promotion places in the Championship.
Blackburn scored a late equaliser to draw 1-all with fellow strugglers Portsmouth.