Liverpool fell to their 4th straight Premier League defeat last night.
Keith Andrews lead his Brentford side to victory with a 3-2 defeat of the champions at the G Tech Community Stadium.
It leaves the champions 6th in the league, below Manchester United who are fourth.
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They survived a fightback from Brighton to come away with a 4-2 victory at Old Trafford yesterday.
Arsenal can move 5 points clear at the top with victory against Crystal Palace.
That's one of four games down for decision at 2pm.
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Elsewhere, Manchester City travel to Aston Villa, Bournemouth play host to Nottingham Forest and Wolves come up against Burnley.
The late game sees Everton battle it out with Tottenham at 4:30pm.
