The vaccine hub at the Kerry Sports Academy in Tralee will be closed this week.
It's being reported this is due to a shortage of vaccines.
Staff were informed last Friday that the Tralee centre would be closed this week.
The HSE says all available vaccine scheduled for use in the Tralee centre have been fully utilised, and adds it's anticipated the supply will remain steady and increase over the coming weeks.
A spokesperson for the HSE says the vaccination clinic in Tralee has been open over the past few weeks on specific days to vaccinate members of the public identified by clinicians as being in the Cohort 4 category.
The Killarney vaccination clinic will be used for the first time this week and will also vaccinate some Kerry-based patients at Cork University Hospital.
The HSE says vaccinations will return to the Tralee venue the following week and it's anticipated both Kerry venues will provide service as the weeks progress.
Fianna Fáil councillor Mikey Sheehy says has contacted the HSE to find out exactly why the Tralee centre is closed this week, but believes it's a supply issue.
Cllr Sheehy says the HSE are getting people vaccinated as quickly as possible, when the supply is there.
However, he says the closure of the Tralee vaccination hub this week this is very disappointing news for everyone in the county: