The former Talbot Grove building in Castleisland has been put on the market.
The five-bedroom property including the land, which is 5.45 acres in total, is up for €525,000.
There's also the option to purchase it in two separate lots; the house on 3 acres (€375,000) or 2.45 acres of land (€150,000).
The alcoholism and addiction rehab treatment centre, now known as The Grove, relocated to Ardfert to comply with social distancing guidelines last August.
Michael Coghlan of Sherry FitzGerald Coghlan, Killarney is handling the sale.