Dan Sheehan will captain the Lions in Saturday's match against the Western Force.
Sheehan's Ireland and Leinster teammates Garry Ringrose, James Lowe, Joe McCarthy and Josh van Der Flier will also make their debuts for the tourists.
Munster captain Tadhg Beirne starts at blindside flanker with Connacht's Mack Hansen on the right-wing.
Tadhg Furlong has been picked at tight-head with Scotland's Finn Russell named to start at out-half.
Andrew Porter, Ronan Kelleher and Jack Conan are among the replacements.
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The Western Force have selected six current Australian internationals for Saturday's game.
Tom Robertson, Darcy Swain, Nick Champion de Crespigny, Nic White, Dylan Pietsch and Ben Donaldson will all start before linking up with the Wallabies.
Kurtley Beale has been ruled out with a hamstring injury.
Lions team v Western Force:
15. Elliot Daly (Saracens/England) #822
14. Mack Hansen (Connacht Rugby/Ireland) #867
13. Garry Ringrose (Leinster Rugby/Ireland)
12. Sione Tuipulotu (Glasgow Warriors/Scotland) #863
11. James Lowe (Leinster Rugby/Ireland)
10. Finn Russell (Bath Rugby/Scotland) #835
9. Tomos Williams (Gloucester Rugby/Wales) #866
1. Pierre Schoeman (Edinburgh Rugby/Scotland) #868
2. Dan Sheehan (Leinster Rugby/Ireland) (c)
3. Tadhg Furlong (Leinster Rugby/Ireland) #818
4. Scott Cummings (Glasgow Warriors/ Scotland) #869
5. Joe McCarthy (Leinster Rugby/Ireland)
6. Tadhg Beirne (Munster Rugby/Ireland) #838
7. Josh van der Flier (Leinster Rugby/Ireland)
8. Henry Pollock (Northampton Saints/England) #865
Replacements:
16. Ronan Kelleher (Leinster Rugby/Ireland) #864
17. Andrew Porter (Leinster Rugby/Ireland)
18. Will Stuart (Bath Rugby/England)
19. Ollie Chessum (Leicester Tigers/England)
20. Jack Conan (Leinster Rugby/Ireland) #839
21. Alex Mitchell (Northampton Saints/England) #860
22. Huw Jones (Glasgow Warriors/Scotland)
23. Marcus Smith (Harlequins/ England) #855
