Tottenham remain unbeaten in the Premier League this season. Harry Kane was among the goal scorers in their 2-1 win over Fulham.
Chelsea came from behind to beat London rivals West Ham by the same scoreline - though David Moyes' side had a late goal ruled out by VAR.
Liverpool dropped points for the fourth time in this campaign as the Merseyside derby ended goalless.
Ivan Toney scored a hat-trick for Brentford as they eased to a 5-2 victory at home to Leeds.
Managerless Bournemouth came from two behind to win 3-2 at fellow newly promoted club Nottingham Forest.
Wolves got their first victory as they edged Southampton 1-nil.
Newcastle and Crystal Palace played out a goalless draw.
Defending champions Manchester City can end the day top of the table if they seal all three points against Aston Villa - who are out to avoid a fourth straight loss - in the late game.
