Crystal Palace begin their bid to retain the FA Cup this lunchtime.
Oliver Glasner's side have a third-round clash at non-league Macclesfield, with kick-off at quarter-past-12.
At the same time, there's an all-Premier League encounter with Everton hosting Sunderland.
Among the ties underway at 3, Newcastle face Bournemouth,
Keith Andrews takes his Brentford side to Hillsborough to face the Championship's bottom side Sheffield Wednesday,
Fulham host Middlesbrough, and Manchester City are at home to League One outfit Exeter City, who have former Sligo Rovers midfielder Jake Doyle-Hayes in their squad.
At quarter-to-six, Tottenham welcome Aston Villa to North London.
Wrexham caused the first big FA Cup upset of the third round - after knocking out Nottingham Forest in a penalty shootout last night.
Republic of Ireland midfielder James McClean missed his penalty attempt for the Championship side, but they still won on spot kicks.
The match finished 3-all after extra time.