Southampton have sacked manager Ralph Hasenhuttl after four years in charge.
Yesterday's 4-1 Premier League defeat at home to Newcastle left them third from bottom in the table.
The Saints are one point from safety having won just once in their last nine matches.
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First Team lead coach Ruben Selles is set to take charge for Southampton's League Cup clash with Sheffield Wednesday on Wednesday.
Luton manager Nathan Jones has been given permission to talk to Southampton.
