2010 World Cup winners Spain get their campaign underway this evening.
Shamrock Rovers defender Pico Lopes is expected to line out against them, as they face Cape Verde in Atlanta.
Lopes knows they'll be up against it when taking on the European champions, but he says they're determined to make it tough for their opponents
Elsewhere, Seattle plays host to the clash of Egypt and Belgium, before the meeting of Saudi Arabia and Uruguay in Miami.
Overnight, Ivory Coast left it late to pick up three points against Ecuador - Amad Diallo's last-gasp winner secured a 1-0 win for the African side.
Elsewhere, Sweden eased past Tunisia with a 5-1 win - with Liverpool's Alexander Isak and Arsenal's Viktor Gyokeres among the goalscorers.