Premier League Leaders Manchester City will look to follow up on their impressive Champions League win over PSG during the week this afternoon.
They take on Crystal Palace at Selhurst Park at lunchtime.
Going into the game the visitors are 10 points clear at the top of the table while Roy Hodgson's side are 13th.
At 3-o'clock Brighton will be hoping for a win against Leeds at the Amex as they continue their fight against relegation.
At half-past-5 there's a west London derby between Chelsea and Fulham at Stamford Bridge.
Scott Parker's side need three points here to have any hope of avoiding the drop.
And the late game is between Everton and Aston Villa with kick-off at Goodison Park at 8-o'clock.
Last night Leicester City and Southampton drew 1-1 at St. Mary's.
The point means the Foxes remain third and are eight points clear of fifth placed West Ham.
Meanwhile it was announced that each Premier League club will get to play one more game in front of their own fans before the end of the season.
A midweek round of fixtures has been moved to after May the 17th, when the English Government's due to further ease coronavirus restrictions.
A maximum of 10-thousand fans should be able to attend the matches.
