Munster suffered back-to-back defeats in the URC last night.
A penalty try ultimately proved the difference, as the Men in Red went down 26-21 to Cardiff at the Arms Park.
This afternoon, Connacht are in Johannesburg in desperate need of a win against the Lions at 3.
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Ronan Kelleher captains Leinster for the first time as they travel to the Scarlets for a 5.15 kickoff.
At 7.35, Ulster go toe-to-toe with a star-studded Sharks side in Belfast.