Third placed Nottingham Forest remain on course for Champions League qualification after beating Manchester United 1-nil.
Wolves got past West Ham by the same score to pull 12 points clear of the relegation zone.
Liverpool can take a step closer to the title with victory in tonight's Merseyside derby against Everton at Anfield.
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Manchester City and Newcastle have hopes of climbing into the top four ahead of their games with Leicester and Brentford respectively.
Brighton against Aston Villa is a clash of two sides chasing European qualification, while Bournemouth still retain hopes of continental football ahead of their match with Ipswich.
Bottom side Southampton host Crystal Palace.
