Scrum-half Conor Murray and centre Chris Farrell have been ruled out of Munster's Pro14 Rainbow Cup meeting with Cardiff Blues.
Murray has a leg injury but the province say he's expected to be available for the next round away to Zebre on June 11th.
Farrell is out of Friday's game as he continues his rehab for a groin injury.
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Meanwhile, ex-Munster lock Ian Nagle has announced his retirement from rugby.
The 32-year old also had spells at Leinster and Ulster and was most recently with Zebre in Italy.
Nagle represented Ireland at Under-20 level, and played for the Emerging Ireland side.