Defending champion Madison Keys is out of the Australian Open after losing to Jessica Pegula in straight sets overnight.
Elsewhere in the last 16 of the women's singles, there were wins for Elena Rybakina and Amanda Anisimova.
In the men's draw, Jannik Sinner leads Luciano Darderi by a set to nil in the match currently on court.
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Lorenzo Musetti is safely through to the quarter finals after a straight sets victory over Taylor Fritz in Melbourne overnight.
Novak Djokovic received a walkover from Jakub Mensik, who was forced to withdraw due to injury ahead of their last 16 tie.
