The Republic of Ireland Under 21's lost 2-0 to Italy in Group F of the European Qualifiers.
Northern Ireland beat Lithuania 1-0 at Windsor Park in their FIFA World Cup qualifier.
Elsewhere England beat Albania 5-0 at Wembley Stadium where Harry Kane scored a hat-trick.
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Scotland meanwhile beat Moldova 2-0 away from home to guarantee a play-off spot.
Goalkeeper Craig Gordon saved a late penalty in the game to ensure a clean sheet.