Connacht have suffered an injury blow with Byron Ralston ruled out for the remainder of the season.
The Australian back sustained a knee injury against Munster.
Connacht say the injury is 'significant' and Ralston is set to undergo surgery next month before beginning a rehab programme.
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Organisers of the new Nations Championship have confirmed the tournament will finish with a finals weekend at Twickenham next November.
The new biennial competition will see matches between northern hemisphere and south hemisphere countries take place across the summer and autumn international windows.
Six teams from either side of the equator will take part, with Ireland set to begin their campaign against Australia on July 4th.