Arsenal are nine points clear at the top of the Premier League after beating Everton 2-nil.
Nearest challengers Manchester City, who still have a game in hand, slipped-up with a 1-all draw at strugglers West Ham.
The Hammers are now out the bottom three.
Chelsea missed the chance to go third as they lost 1-nil at home to Newcastle.
Brighton got past Sunderland by the same score, while it finished goalless between Burnley and Bournemouth.
Manchester City and Aston Villa will look to capitalise on Chelsea's loss to Newcastle in the race for Champions League qualification this afternoon.
United welcome Villa to Old Trafford in a clash of third against fourth.
Liverpool can move into the top-five if they beat struggling Tottenham at Anfield.
Nottingham Forest are a point below Spurs and inside the relegation zone ahead of their match against Fulham.
While Leeds go to Crystal Palace.
