With Liverpool not in action until tomorrow, Arsenal can move within four points of the Premier League leaders at lunchtime.
The Gunners travel to Leicester City for a half 12 start.
Five games get underway from 3 o'clock.
Manchester City and Newcastle United are level on points ahead of their meeting at the Etihad Stadium.
Nottingham Forest can tighten their grip on third - they're away to Fulham.
Evan Ferguson could make his West Ham debut, when Brentford come to the London Stadium.
It's a South Coast derby at St. Mary's, where Southampton host Bournemouth.
Aston Villa entertain Ipswich Town.
The evening game sees Everton travel to Crystal Palace for a half 5 start.
Brighton were comfortable 3-0 winners over Chelsea, beating the Blues for the second time in six days.