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Chelsea aim to move to within two points of the Premier League's top three with victory at Newcastle this lunchtime.
Manchester City can climb to the summit - for a short time at least - by winning at home to West Ham.
Leaders Arsenal travel to Everton in one of two evening kick-offs, which also sees Leeds welcome Crystal Palace.
Elsewhere, bottom side Wolves will hope their winless start in the league will end when they host Brentford, while fellow strugglers Burnley visit Bournemouth and Sunderland make the long trip to Brighton.
Tottenham Hotspur go for a third home victory in a row in all competitions when they face Liverpool in the teatime fixture.
Liverpool midfielder Curtis Jones has revealed Mohamed Salah apologised to his team-mates after his controversial comments two weeks ago.
The Egypt forward was removed from selection for his club's Champions League win at Inter Milan after saying he no longer had a relationship with boss Arne Slot following a 3-all Premier League draw at Leeds.
Jones believes that frustration comes with wanting to win.
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There was one game in the EFL Championship last night.
Republic of Ireland striker Adam Idah got the winner as Swansea City beat Wrexham 2-1 in a Welsh derby.
Leaders Coventry are at Southampton this afternoon in one of three early kick-offs, while fellow promotion-chasing Millwall travel to Blackburn and Preston host Norwich.
Second-placed Middlesbrough aim for a fifth straight win at Bristol City.
Of the other teams in the play-off places, Ipswich welcome bottom side Sheffield Wednesday and Hull have West Brom.
Stoke could end the day in the top six and are at Watford, while Leicester go to QPR, who also have 31 points.
At the other end of the table, Oxford visit Charlton, Portsmouth are away to Derby and Sheffield United host Birmingham.
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Motherwell have the chance to end the day third in the Scottish Premiership.
They'd do that with a victory at home to Dundee, as the top three don't play until tomorrow.
Hibs - in fifth - are at Dundee United, while Falkirk aim to move level on points with sixth-placed Aberdeen when they take on strugglers Kilmarnock.
Elsewhere, League Cup winners St Mirren host bottom side Livingston.
