Manchester City have suffered just their second Premier League defeat of the season in losing 2-1 at home to Brentford.
Arsenal can go five points clear at the top with a victory at Wolves this evening.
Tottenham are up to third-place after a comeback 4-3 win against Leeds.
Darwin Nunez scored twice in Liverpool's 3-1 victory against Southampton.
Bournemouth beat Everton 3-nil, Leicester were 2-nil winners at West Ham while Nottingham Forest moved off the bottom of the table with a 1-nil victory against Crystal Palace.
Newcastle host Chelsea at half-five.