Chelsea needed extra time to get their defence of the Women's FA Cup off to a winning start with a 3-1 victory over rivals West Ham,
The holders' fourth round tie was level at 1-all after 90 minutes.
Record-winners Arsenal avoided an upset with a comfortable 5-nil victory against Championship strugglers Watford, Tottenham came from 2-nil down to beat second-tier Sheffield United 3-2 and National League Newcastle suffered a 4-nil defeat to Manchester United.
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Luton - the lowest ranked team left in the competition - were thrashed 6-nil at home to Brighton.
