Gardai say the N21 outside Abbeyfeale on the Castleisland road has reopened following a four car crash.
The incident occurred at shortly before 2pm.
Four ambulances attended the scene and its understood that a number of passengers are being treated for minor injuries.
Motorists travelling from the Castleisland side were being diverted to the Hill Road.
Gardai say the N21 has now reopened.